Rhabdomyomatous mesenchymal hamartoma presenting as a polypoid mass in a neonate
نویسندگان
چکیده
Rhabdomyomatous mesenchymal hamartoma (RMH) is a benign, rare entity with approximately 70 cases reported since the 1980’s [1]. This was first described in 1986 as a striated muscle hamartoma [1]. It has also been reported as congenital midline hamartoma and hamartoma of cutaneous adnexa and mesenchyme [1]. RMH most often presents as a solitary lesion on the head or neck of an infant [2]. The lesion is confined to the dermis and subcutis, and consists of mature skeletal muscle, adipose tissue, adnexae, and nerve bundles [3-5]. The clinical presentation is variable and consequently the differential diagnosis is vast, including acrochordon, accessory tragus, hemangioma, rhabdomyoma, neurofibroma, and nasal glioma [1,613]. Histopathologic evaluation is requisite for diagnosis. The etiology of RMH is unclear, but some postulate that it is the result of abnormal cell migration of mesodermic tissues during embryogenesis [1,4-6] or a genetic proclivity toward formation of harmatomas [2,11]. Accordingly, it follows that associated developmental anomalies may exist. Although the majority of patients diagnosed with RMH are otherwise healthy Abstract
منابع مشابه
Rhabdomyomatous Mesenchymal Hamartoma Presenting as a Midline Mass on a Chin
A 17-month-old boy was evaluated for a midline mass on his chin. The mass was anchored to the mentalis muscle with a stalk-like structure. The pathological diagnosis of the mass was rhabdomyomatous mesenchymal hamartoma. This is the first report of rhabdomyomatous mesenchymal hamartoma presenting as a midline chin mass in Korean pediatric patients.
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